Pot Compounds Reduce Multi-Drug Resistant Infections, Study Says
Cannabinoids Show =93Exceptional=94 Antibacterial Activity Against MRSA
August 28, 2008 - Novara, Italy
Novara, Italy: The administration of natural plant cannabinoids can
significantly reduce the spread of drug-resistant bacteria, including
methicillin-resistant Staphyloccus aureus (aka MRSA), according to
preclinical data to be published in the Journal of Natural Products.
Investigators at Italy's Universita del Piemonte Orientale and
Britain's University of London, School of Pharmacy *****sed the
antibacterial properties of five cannabinoids - THC, CBD
(cannabidiol), CBG (cannabigerol), CBC (cannabichromine), and CBN
(cannabinol) - against various strains of multidrug-resistant
bacteria, including MRSA.
"All compounds showed potent antibacterial activity," authors
determined. Researchers noted that cannabinoids showed "exceptional"
antibacterial activity against EMERSA-15 and EMERSA-16, the major
epidemic MRSA strains occurring in UK hospitals.
Authors concluded: "Although the use of cannabinoids as systemic
antibacterial agents awaits rigorous clinical trials, =85 their topical
application to reduce skin colonization by MRSA seems promising. =85
Cannabis sativa =85 represents an interesting source of antibacterial
agents to address the problem of multidrug resistance in MRSA and
other pathogenic bacteria."
According to a 2007 study published in the Journal of the American
Medical Association, MRSA is responsible for more than 18,500 hospital-
stay related deaths each year.
For more information, please contact Paul Armentano, NORML Deputy
Director. Full text of the study, "Antibacterial cannabinoids from
cannabis sativa: A structure-activity study," will appear in the
Journal of Natural Products.
updated: Aug 28, 2008
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